4-Why Do We Fall ill

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Why do we fall ill
1)  Our body’s well-being is dependent on the proper functioning of its cells and tissues.
2)  All our body parts and activities are greatly interconnected. Hence dysfunction of any body part
will affect the entire body.
3)  When we are healthy, we are able to perform our physical, mental and social functions well.
4)  Our physical and social environment plays an important role in maintaining good health.
5)  In addition to personal hygiene, public cleanliness should also be maintained for ensuring that
we remain healthy.
6)  Many other factors like financial conditions, availability of nutritious food and social equality also
influence the health of an individual.
7)  A person suffering from a disease is in a state of discomfort.
8)  Being in poor health is different from being diseased.
9)  Symptoms and signs of the disease appear as a result of dysfunction of the affected body parts.
These help to identify the disease that a person is suffering from.
10)  Depending on their duration, diseases may be classified as acute or chronic.
11)  Acute diseases last for a short time and do not cause major health effects. E.g. Common cold.
On the other hand chronic diseases persist for a long time and hence cause prolonged ill health.
E.g. TB of lungs.
12)  Causes of diseases may be immediate (first level cause) or contributory. For e.g. – The immediate
cause of a person suffering from diarrhoea is the causative agent. The contributory causes could
be i) lack of good nourishment or genetic difference (second level cause), ii)
poverty or lack of public services (third level cause)
13)  Diseases  may  be  infectious  or  non-infectious.  Infectious  diseases  are  caused  by  microbes  or
other  infectious  agents  (e.g.  Malaria)  whereas  non-infectious  diseases  have  internal,  noninfectious causes (e.g. High blood pressure).
14)  The infectious agents may be viruses, bacteria, fungi, protozoans or multicellular organisms like
worms.
15)  The type of treatment of a disease depends on the category of the infectious agent.
16)  Organisms belonging to one category will share several important life processes, which will be
different from those of organisms belonging to other categories.
17)  Drugs  working  by  interfering  with  life  processes  of  one  category  of  organisms  will  not  be
effective  against  members  of  another  category.  E.g.  Antibiotics  act  against  bacteria,  but  not
viruses, since viruses do not share bacterial pathways.
18)  Penicillin interferes with bacterial cell wall production, thus killing the bacteria. Due to lack of
cell walls, penicillin does not affect human cells.
19)  Many  infectious  diseases  are  called  ‘communicable  diseases’  since  they  can  spread  from  one
person to another.
20)  Communicable diseases can spread through air, water, food, sexual contact or vectors.
21)  The  droplets released during coughing or sneezing of an infected person causes the spread of
air-borne diseases like common cold, pneumonia, tuberculosis etc.
22)  Air-borne diseases spread quickly in overcrowded and poorly ventilated living conditions.
23)  Water-borne  diseases  like  cholera  spread  when  drinking  water  gets  contaminated  with  the
infectious agents.
24)  Sexual contact causes the spread of diseases like AIDS and syphilis from the infected person to a

English: Simplistic overview of the main viral...

English: Simplistic overview of the main viral infections and the most notable involved species (See also Wikipedia:Virus#Viruses and human disease). Model: Mikael Häggström. To discuss image, please see Template talk:Häggström diagrams (Photo credit: Wikipedia)

healthy one. AIDS virus can also spread through  blood transfusions, use of infected needles or
during pregnancy and breast-feeding by an infected mother.
gory of infectious agent   mples of diseases caused
mon cold, influenza, Dengue fever, AIDS
ria   oid, cholera, tuberculosis, anthrax
infections
zoans   ia, kala-azar
tinal worm infections, elephantiasis
25)  Vectors are intermediate animals causing the spread of disease causing agents from an infected
person  to  a  healthy  person.  For  example  –  Female  mosquitoes  transmit  many  diseases  like
malaria when they feed on the blood of animals and humans.
26)  On entering the body, the infectious agents reach their specific target organs. In certain cases the
target organ is related to their point of entry. For e.g.  –  Typhoid causing bacteria enter through
mouth and reside in gut lining.
27)  In other instances, the target organ of the microbe has no relation to their point of entry. For e.g.
HIV enters through the sexual organs but spreads to all the lymph nodes.
28)  The symptoms of a disease depend on the target organ infected by the microbe. For e.g. cough
and breathing problems are seen when lungs are infected. So based on the signs and symptoms
of a disease, we can get an idea of the target organ of the microbe.
29)  During  infection,  the  body’s  activated  immune  system  sends  specialized  cells  to  destroy  the
microbes, causing inflammation, with associated local effects.
30)  The AIDS causing virus destroys the functioning of the immune system, due to which the body
becomes  unable  to  fight  even  minor  infections.  Ultimately  the  patient  succumbs  to  such
infections.
31)  The severity of a disease is directly proportional to the number of infectious agents present in
body.
32)  An infectious disease can be treated in 2 ways:
i) Reduce the symptoms of the disease by providing treatment ii) Kill the infectious
agent causing the disease.
33)  Medicines used in killing an infectious agent aim to disrupt some pathway of a vital life function
peculiar to that group of organisms. These pathways are not present in other microbial groups or
in humans.
34)  On  entering  human  cells,  viruses  use  our  cellular  machinery  for  carrying  out  all  their  life
processes.  There  are  very  few  virus-specific  biochemical  pathways  that  can  be  targeted  to
produce anti-viral drugs.
35)  The approach of treatment of an infectious disease has three drawbacks:
i)  Recovery of the patient may not be complete in certain cases.
ii)  Treatment requires time; hence the patient suffers from the disease and may be
bedridden.
iii)  The patient serves as the source of spread of infection to others.
36)  It is desirable to prevent a disease than to treat it completely.
37)  There are general and specific ways of preventing diseases.
38)  Infectious diseases can be generally prevented by public health hygiene methods, which aim to
reduce exposure to infectious microbes. Public hygiene measures include providing safe drinking
water, clean environments and adequately spacious conditions for living.
39)  Another general method of preventing infectious diseases requires the availability of sufficient
and balanced diet for the proper functioning of the immune system. The immune system ensures
that we do not develop a disease each time we are exposed to an infectious agent, by destroying
the agent before it multiplies greatly.
40)  During smallpox epidemics, it was noted that people who survived after suffering form smallpox,
did not get infected with it again. Such observations led to the birth of immunization, which is a

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specific method of preventing infectious diseases.
41)  The principle of immunization is based on the memory of the immune system on encountering
an infectious agent. On subsequent encounters with the same or related microbe, the response
of the immune system is multiplied greatly, leading to quick elimination of the infection.
42)  During immunization, a vaccine (containing weakened or killed pathogen or a specific part of the
pathogen) is introduced into the body to fool the immune system into remembering a particular
infection. Hence the body does not suffer even on further exposures to that pathogen or its close
relatives.
43)  Nowadays, vaccines preventing many infectious diseases like tetanus, polio and measles are used
extensively especially in child health immunization programmes.
44)  Everyone in the community should have access to public hygiene and immunization for effective
prevention of infectious diseases.

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